Most Prevalent DNA Viruses of Herpesviridae Family in Relation to Skin Cancer among Nepalese People

  • R. P. Aryal Central Department of Microbiology,Tribhuvan University, Kritipur, Kathmandu
  • S. K. Adhikari Central Department of Microbiology,Tribhuvan University, Kritipur, Kathmandu
  • M. C. Lee Department of Pathology, Patan Hospital, Lalitpur
  • Y. Kimula Department of Pathology, Patan Hospital, Lalitpur

Abstract

The possible correlation of Herpes Simplex virus type l(HSV l), Herpes Simplex type 2 (HSV 2), and Epstein Barrvirus (EBV) with skin cancer was studied by using Enzyme Linked Immunosorbent Assay (ELISA) technique based on virus specific antibodies produced by immune responses. Serums of 15 clinically diagnosed histopathologically confirmed skin cancer patients were studied for the presence of IgM antibodies against theseviruses with reference to one hundred control cases. There were no correlations between the viruses HSV 1, HSV 2, and EBV with the skin cancer of the type squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and melanomamost commonly found skin cancer cases in Nepal